DFRPG adventures I can see falling into the Buffy, "Monster" a week or BBETTCAWDTW (Big Bad Evil Thing That Can And Will Destroy The World" a Week structure. This week the Shroud of Turin, next week the actual Grendel and the week after that soe introspective character moments involving Sweet from Once More, With Feeling.
But, that can work in a DF game and it will never get boring.
IMHO, the key to a Dresdenified Adventure is the Dresden Tongue-in-cheek/Dry/Black Humor that comes with Harry Dresden's world view.
In D&D Adventures, you can have the monster destroying the town adventure plot and the adventure will work. It's an average day.
In Eberron, you can do that same Adventure with a subplot that adds dark overtones to it.
In Cyberpunk, you can do this, but the likelyhood the characters will survive is tanked unless they get really creative.
In the Dresden Files, you have to combine all three of these approaches and make it funny.
Often times the players shouldn't add a pop culture reference or laugh, but they just gotta....
In fact, it's a requirement....
However, no 2 DMs will approach the same material the same way. Everybody likes different parts of Dresden. Some people like the Phillip Marlowe aspect, wanting to make their game dark or like Angel. While others like the humor and have a serious threat in an awkward situation.
Example Adventure(This sounds like the beginning of a Dresden Book): A new Panda has been brought into the City Zoo. However, the Zookeeper skimped on the money(Pandas are expensive) and didn't want to handle the Chinese Government, so he got a Panda through a shady dealer. The Panda they ended up with was a Demon that was dormant, but now has run amok in the zoo. The players begin the adventure being called in by the Murphy Surrogate to handle the Demon. They find the Demon sleeping in the middle of the Zoo, dead bodies all around.
Some DMs will feel inclined to downplay the humor, going for more of the, "it's a big scary thing running around the zoo killing people. Not funny" Players: "But it's a panda!" DM: "Blood drips from its teeth..."
While some DMs will instead go for an adventure in a more off the wall style. If I was going for that kind of game I would follow the previous details with the following:
The Demon Panda snores as one of the Zookeepers crawls away to safety. He makes a sound. The Panda awakens and groggily tosses him like a ragdoll. All the while, the Panda yells, not growls, but yells in Cantonese and goes back to sleep.
Even if a PC doesn't speak Mandarin or Cantonese they figure the Panda basically said, "QUIET! SHUT UP! QUIET! I SAID QUIET! WHAT'S THE MATTA', YOU DEEF OR SOMETHIN'?" If someone does speak Cantonese, they know he said exactly that. The players will die laughing and end up angering the panda and starting the adventure.
(Extra points to the person who knows the origin of that joke...)
IT all depends on the DM, the group and the interpretation of Dresden you like.
