I was kidding on the Thor comment, I am an old guy, well the same age group as Harry, and the one thing I love about TV and Movies now is that it is harder for a stigma to Stick on actors... I am a firm believer that Type casting is wrong, to Not hire someone because they were known as a character is wrong. More than a few from when I was coming up are making a come back in a big way.
I believe that if a tv show, or movie were in the works, Casting Harry is going to be the hardest part. No One who is already famous fits the mold right. I would hope that the casting director would spend a lot of time, and cast hard because I believe in my heart of hearts that our Harry is going to be an Unknown actor.
On the other hand, very few actors these days seem to break out of the mold of the character that made them famous. So few can completely disappear into the role. Then too, certain actors get cast repeatedly as the same type of character, to the point where they are always seen as that character.
A good example of this is Bruce Willis, who seems to play a lot of renegade cops (not necessarily dirty, just cops that don't like to play by the rules) -- Die Hard, 16 Blocks, Last Boyscout
His character in Unbreakable was of a similar mold, but not quite the same, and he's played a few other characters that were different enough, but they're almost always action movies.
Mel Gibson plays a number of characters with strong similarities to Martin Riggs (Lethal Weapon) -- Tragic past is a common theme. That said: He did a fabulous job as Lt. Gen. Hal Moore in We Were Soldiers.
Johnny Depp is a decent actor, but lately it seems like every movie he's in becomes Johnny Depp Does Stuff (f/ex. Alice in Wonderland, Charlie and the Chocolate Factory, Sweeney Todd) He was great as Jack Sparrow. I liked how he played an a$$hole in Once Upon a Time in Mexico and his earlier movies like Edward Scissorhands and Benny and Joon were shear genius. It's unfortunate that film-makers seem to see a need to tailor roles to fit him like Stanley Kubrick did for Jack Nicholson in The Shining, he's capable of so much more.
I'm going to do something crazy, and suggest Tilda Swinton as Mab.
She was excellent as the Witch in The Lion, the Witch and the Wardrobe. She would run a close second to Michelle Pfeiffer for me.