I think the question that concerns our group is: Can a player be forced to "Choose?" Can a player be forced to make their character non-playable? An NPC? Even if it is part of a story, like with Changelings...
The whole vibe from DF RPG and FATE system in general tells me... Probably not. If a player doesn't want their character to become an NPC, then they can make all the right choices to prevent that from happening by the rules as written.
Changelings are Scions. So, that's what brought the question up. Changelings have an explicit Choice to make when playing the game. Remain mortal and have some nifty powers or... become Fae and get some more nifty powers. The rules say that the former is a PC and the latter is an NPC. We're wondering if other Scions have drawback and, even in the case of Changelings, can that Choice be forced upon you?
I would say that the Choice can't be forced, with a caveat. Narratively, if the character keeps drawing on their nonhuman heritage and developing more and more powers, they're going to get to the point where they effectively make their Choice and become an NPC. This isn't forced - this is due to actions the character took, the Choice the character made to keep drawing on and developing those powers despite knowing where that path would lead. At any point up until they become an NPC, though, they can make the opposite Choice and become a pure mortal.
Mechanically, a GM can compel a PC to take actions that lead to the character making their Choice, but the player can refuse the compels as long as they have Fate Points to spare. And, as others have said, it's bad form for a GM to compel a character to become an NPC.
The caveat is this: In the case of Changelings, there is one known way to force someone's Choice - arrange for them to receive the mantle of a faerie queen/mother/lady. However, to do this, you would need to A) Be able to kill one of the most powerful beings of faerie and B) Arrange it so that the Changeling was the closest possible vessel for the mantle. So...it's extremely unlikely to come up in play.
This is pure speculation on my part, but it's possible other scions might be forced into their Choice the same way, depending on how gods' mantles work. In the highly unlikely event that a god is killed, would the god's mantle then settle on his nearest scion, effectively making their Choice for them?