These are all excellent and valid points. However, with my apologies to the guys and gals over at Best Brains, "Just repeat to yourself it's just a book, I should really just relax..."   

When next the baddies are trying to get through my wards, I must remember that I am not French, I do not have an outrageous accent, my apartment is not the castle of my master Louis de Lombard, I have not already got one, and the bad guys are not daffy English Knnnnnnnn-iggets. Even if it's Morgan and his door opening request is a silly thing.

I'd definitely Dresden-ify my hometown of Buffalo, New York. Since it's solidly Rust Belt, there's umpteen-bajillion fun places to stick monsters, like the old abandoned steel plants, decaying empty warehouses and grain elevators, Love Canal, dumps with Manhattan Project leftovers in them, and a city hall that's a phallic symbol designed by Gozer Worshipers. It won't be a happy place to set a game, but it will be atmospheric.