Once I have the book/game? I have never play a RPG or an online game.
It's going to be big, and hopefully not too intimidating. The FATE system runs pretty smoothly, and is definitely "free style" enough where you can customize and make it your own campaign.
If you've never played an RPG before, you might want to give it a try before the "real thing" comes out. You can download
FATE 3 (which isn't quite the same as the RPG, but similar in many ways) for free, or could buy
Spirit of the Century (same author and similar mechanics) just to see how it plays.
Another game that gets a lot of Dresden-love is
Unisystem, which can be found in the form of the
Buffy the Vampire Slayer RPG. Similar ideas, lots of TV source material to draw from, and a lot of fun to play.
There are other RPGs out on the market, many as free downloads. I think if you try some of them first you'll find that it's easier to figure out how to play DFRPG. Also, RPGs are a great hobby. I've gotten my wife and kids playing, and it makes for great family togetherness.....