I think Ancient Mai did mid-life crisis sometime around the signing of the Constitution.
How do you know? If she gathers enough power and uses it she can go on for centuries.
Besides midlife crisis, despite its name, has more to do with the sudden realisation that everything ends and that you are not immortal and don't have everlasting youth.
You do things now because later is to late.
Wizards get that much later than normal people.