I don't see it as an either-or thing. Here's a concept I had for a modern day version of Jacob, who wrestled Uzziel and won, skinned for a 30 skill 8 refresh game
5 athletic, might
4 conviction,fists
3 end, intimidate
2 alert, whatever you like
1 whatever you like
-2 Righteousness
-1 Holy touch
-4 SU toughness (not tied to human form, su stuff just slides off him)
+3 Catch (mortal weapons/fists without any supernatural assistance)
2 Human form (powers only manifest against supernatural opponents, to equalize. This is a glow like that around Mouse's muzzle, it can't be hidden, can't be controlled and likely there are aspects to compel action against appropriate foes too. Given the source we might have glowing, phantom wings, halo or whatever)
(minor talents with < 5 refresh of power get only inhuman levels of power, those with <3 refresh get only su strength, those with 1 or less refresh get only claws)
-4 SU strength (human form limit means only for direct attacks on supernatural or to overcome obstacles separating you from such an enemy)
-1 Claws (same limits as strength)
This guy was built to be a wrestler, and do pretty significant stress in a grapple against a supernatural opponent. If folks don't have powers his raw skills are generally plenty to win anyway. For him, his powers were all about equalizing, so an ogre who didn't use his supernatural strength could punch him and bypass toughness, for example. Without the desire for holy touch and claws you could fit in supernatural recovery, or eliminate the human form weakness, where he can't control his powers.
He's got fairly respectable offense (6 fists, 6-7 stress for strength-oriented attacks, 7-1=6 might, 5-6 stress in a grapple as supplemental action depending on if his opponent is affected by Holy Touch), he's pretty durable (high athletics plus su toughness against most high shift attacks, and nothing stops him from wearing body armor against mortal-weapon attacks), he's got intimidate for taunting and social attacks at a respectable level. Should you need some kind of weapon to beat a catch or to handle a specific situation, turning on Righteousness lets you do weapons skill (or guns or drive or a social skill) with Conviction, and he can back it with SU strength.