How about these two for Harry and Thomas? Put some dark hair on 'em and I'd be sold. In fact, this is how I always pictured Thomas before remembering he's got dark hair as well.
I've never seen Queer as Folk, so I wouldn't have a hard time watching these two be brothers instead of lovers, but that might be different for some of you!
Also, Anna Paquin for Anna Valmont. Or, Heck, Murph. Nearly.