Like... if a PC were knocked out with chloroform, I would allow them to use a fate point to wake up at an opportune time to make their escape.
If they're taken out, they don't get that luxury.
If someone wants a PC taken alive, that's plot territory, in my book, and if a PC is taken out of the fight this way (but not formally Taken Out), I'm inclined to treat this method as a plot Compel (not a traditional Compel) and give them a Fate Point for their trouble. They would "awaken" when the plot train arrived in the station.
But if the chloroform is simply a weapon someone is using, and not part of an engineered plot, then letting them shrug it off sooner with a Fate Point would either be a waste of a Fate Point, or a good excuse for a revelation.