An obvious theme for characters, in my opinion. How would different video games stat out?
Fable seems simple, with Strength, Toughness, a bit of Speed and Recovery, Channeling or Evocation for the magic, and lots of stunts in some of the three branches of fighting, Strength, Skill, and Will. High Weapons or Guns (bow, perchance), throw in a bit of the magical skills.
Assassin's Creed would run either as Pure Mortal or maybe a Scion, what with Eagle Vision and some of the things a character survives.
Crackdown is all of the Strength, Speed, Toughness, Recovery, maybe a Claws to represent the 'iron' fists they have. Then Guns and Explosives stunts.
Overlord could make a good BBEG, what with Domination, Supernatural Toughness and Strength, Evocation, and lots of Minions.
What others would be fun?