Weapon:2 is usually a pretty safe call, but I'll let Lenny speak to this; I'm clueless about firearms.
Just because I sleep with a shotgun by the bed... sheesh, Fred.
My honest gut answer is, "I'd need to know why it matters." Real-life combat ballistic performance is a hideously complicated affair, so pretty much, any attempt at verisimilitude is going to fail spectacularly.
However, I can tell you that when I wrote down "oversized pistols", I was thinking of shit like the Desert Eagle, the Freedom Arms .454 Casull, the Thompson Contender in any rifle caliber, basically any of those pistols where one might look at it and wonder about the practical wisdom of putting a round that powerful into that small a frame.
Wikipedia says, "In its full-powered form, [the .44 magnum round] produces too much recoil and muzzle blast to be suitable for a police weapon as it makes rapid fire difficult and strenuous on the users' hands; in particular for shooters of smaller build or with small hands."
Later, it also says that the round is suitable for taking out brown bears.
I leave the decision up to you.